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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences Tranexamic acid impurity B
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
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Medchemexpress LLC 4-(dimethylamino)-1-(2-methoxyquinolin-3-yl)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol | 2122862-01-3 | 5mg
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Bedaquinoline impurity 13 is an impurity of Bedaquinoline
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Sigma Aldrich Fine Chemicals Biosciences Terfenadine impurity A European Pharmacopoeia (EP) Reference Standard | 43076-30-8 |
Terfenadine impurity A European Pharmacopoeia (EP) Reference Standard | Mol Wt: 469.66 | 43076-30-8 |
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Sigma Aldrich Fine Chemicals Biosciences Ketorolac Related Compound C United States Pharmacopeia (USP) Reference Standard | 113502-52-6 | 20MG
Ketorolac Related Compound C United States Pharmacopeia (USP) Reference Standard | Mol Wt: 225.24 | 113502-52-6 | 20MG
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Medchemexpress LLC N-methyl-2-nitroaniline | 612-28-2 | MFCD00007090 | 10g
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Telmisartan impurity 2 is an impurity of Telmisartan (HY-13955)
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Medchemexpress LLC Berberine chloride hydrate | 68030-18-2 | 99.8% | 389.83 | 1 ML
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Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid that acts as an antibiotic. It induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase, and possesses antineoplastic properties. It also has antineoplastic properties.
- Has potential inhibitory effects on the proliferation of four colorectal carcinoma cell lines LoVo, HCT116, SW480, and HT-29.
- Induces a time- and dose-dependent inhibition of LoVo cell growth.
- Exposure leads to accumulation of LoVo cells in the G2/M phase.
- Suppresses cyclin B1, cdc2, and cdc25c protein expression.
- Inhibits the growth of human colorectal adenocarcinoma in vivo.
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Apexbio Technology LLC Decitabine (NSC127716, 5AZA-CdR)(Synonyms: 5-Aza-2'-deoxycytidine, 5-Azadeoxycytidine, 5-AZA-dC, DAC, Dacogen, Dezocitidine, NSC 127716, 5-AZA-CdR), 10mM (in 1mL DMSO), CAS: 2353-33-5.
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Decitabine (NSC127716 5AZA-CdR CAS 2353-33-5) is a cytidine analog that regulates gene expression through inhibition of DNA methyltransferases Upon incorporation into DNA during replication it covalently binds to DNA methyltransferase enzymes leading to reduced DNA cytosine methylation Independent of promoter methylation status decitabine alters histone modifications increasing histone H3 lysine 9 acetylation and histone H3 lysine 4 methylation at specific tumor suppressor gene loci thus reactivating transcriptionally silenced genes It is widely used in biomedical research as an epigenetic modulator particularly in the context of hematopoietic malignancies and solid tumors
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Medchemexpress LLC Rivaroxaban impurity 68 | 845729-41-1 | 99.9% | C10H10N2O4 | 250 MG
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Rivaroxaban impurity 68 is an impurity of Rivaroxaban (HY-50903).
- For research use only
- Not sold to patients
- Solid appearance
- Stable under recommended storage conditions
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Medchemexpress LLC Ruxolitinib (S enantiomer) | 941685-37-6 | 99.6% | C17H18N6 | 200 MG
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Ruxolitinib (S enantiomer), also known as S-Ruxolitinib, is the S-enantiomer of Ruxolitinib and acts as an orally active, potent JAK inhibitor.
- In vitro: suppresses IFNβ-induced expression of ISG, IFIT, and IFITM in human small airway epithelial cells (SAECs) at a concentration of 10 μM for 12 hours.
- In vivo: reduces hematopoietic cell expansion in myeloproliferative neoplasms (MPNs) in female wild-type C57BL/6J or Nes-gfp27 mice when administered via oral gavage at 30 mg/kg, twice per day for 8 weeks.
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Selleck Chemical LLC Doxazosin Mesylate S1324-50mg
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Doxazosin a quinazoline-derivative selectively antagonizes postsynaptic 1-adrenergic receptors used in the treatment of high blood pressure and urinary retention associated with benign prostatic hyperplasia
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Selleck Chemical LLC Boceprevir S3733-5mg
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Boceprevir (EBP 520 SCH 503034) is an oral direct acting hepatitis C virus (HCV) protease inhibitor with Ki value of 14 nM for NS3 It is used in combination with other antiviral agents in the treatment of chronic hepatitis C genotype 1
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Apexbio Technology LLC Labetalol HCl 32780-64-6 10mM (in 1mL DMSO)
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Labetalol HCl (CAS 32780-64-6) is a small molecule antagonist targeting - and -adrenergic receptors It selectively inhibits -adrenergic receptors on vascular smooth muscle preventing adrenergic-mediated vasoconstriction Concurrently Labetalol HCl exhibits non-selective inhibition of -adrenergic receptors in cardiac and bronchial tissues reducing heart rate cardiac contractility cardiac output and arterial blood pressure Due to these vasoactive and cardioregulatory effects it is frequently utilized in research related to cardiovascular physiology hypertension and adrenergic signaling pathways
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Sigma Aldrich Fine Chemicals Biosciences Polyethylene glycol 400 United States Pharmacopeia (USP) Reference Standard | 25322-68-3 | MFCD00081839 | 1G
Polyethylene glycol 400 United States Pharmacopeia (USP) Reference Standard | 25322-68-3 | MFCD00081839 | 1G
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Cayman Chemical S S-hydroxy Bupropion hydroc
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An active metabolite of bupropion; inhibits dopamine and norepinephrine but not 5-HT reuptake in HEK293 cells expressing the human transporters (IC50s = 0.63, 0.241, and >100 µM, respectively); an antagonist of α3β4-, α4β2-, α4β4-, and α1β1 subunit-containing nAChRs (IC50s = 11, 3.3, 30, and 28 µM, respectively); inhibits nicotine-induced analgesia in the tail-flick and hot plate tests, hyperlocomotion, and hypothermia in mice (ED50s = 0.2, 1, 0.9, and 1.5 mg/kg, respectively); substitutes for (+)-amphetamine in rats in a two-lever drug discrimination test (ED50 = 4.4 mg/kg)
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Medchemexpress LLC 3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione | 1239986-50-5 | MFCD18917093 | 95.2% | 369.42 | C23H19N3O2 | 10 MG
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(Rac)-Tivantinib is the racemic form of Tivantinib, a selective c-Met tyrosine kinase inhibitor provided for use as an experimental control in biochemical and cellular research. Supplied as a powder with recommended low-temperature storage, it has CAS 1239986-50-5 and a molecular weight of 369.42 g·mol⁻1.
- Racemic isomer suitable as an experimental control in c-Met inhibition studies.
- Powder form allows accurate weighing and formulation of stock solutions.
- Purity typically reported near 95% for research-grade applications.
- Stable under recommended low-temperature storage for extended shelf life.
- Soluble in common organic solvents for preparation of assay concentrations.
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